C0-Occuring Conditions

Comorbidity is defined as the co-occurrence of two or more conditions in the same person. Comorbid conditions in autism commonly include gastrointestinal symptoms, sleep problems, epilepsy, feeding issues, toileting problems, attention-deficit/hyperactivity disorder (AD/HD), anxiety, depression, and mood problems. ICAN publishes research that highlights the significant health, developmental, educational, and social impacts of comorbid conditions.

Published Articles

O’Rourke, N., Haverty, R., Mannion, A., Whelan, S., & Leader, G. (2024). Characterisation of sleep problems in Angelman Syndrome: A systematic review. Review Journal of Autism and Developmental Disorders. https://doi.org/10.1007/s40489-024-00458-x

Leader, G., Coyne, R., Killeen, C., Whelan, S., Tones, M., & Mannion, A. (2024). Factors associated with sleep disturbances in children and adolescents with Angelman Syndrome. Journal of Sleep Medicine. https://doi.org/10.1016/j.sleep.2024.02.038

Mannion, A., & Leader, G. (2023). Relationship between child sleep problems in autism spectrum disorder and parent mental health and well-being. Sleep Medicine, 109, 4 10.

https://www.sciencedirect.com/science/article/pii/S1389945723001788?via%3Dihub

Mannion, A., & Leader, G. (2023). Relationship between gastrointestinal symptoms in autism spectrum disorder and parent stress, anxiety, depression, quality of life and social support. Journal of Autism and Developmental Disorders. In Press. https://link.springer.com/article/10.1007/s10803-023-06110-7

Leader, G., Curtin, A., Shprintzen, R. J., Whelan, S., Coyne, R., & Mannion, A. (2023). Adaptive living skills, sleep problems, and mental health disorders in adults with 22q11.21 deletion syndrome. Research in Developmental Disabilities, 136, 104491. https://doi.org/10.1016/j.ridd.2023.104491

Leader, G., Whelan, S., Chonaill, N. N., Coyne, R., Tones, M., Heussler, H., Bellgard, M., & Mannion, A. (2022). Association between early and current gastro-intestinal symptoms and co-morbidities in children and adolescents with Angelman syndrome. J Intellect Disability Res, 66, 15. Link to article

Leader, G., Gilligan, R., Whelan, S., Coyne, R., Caher, A., White, K., ... & Mannion, A. (2022). Relationships between challenging behavior and gastrointestinal symptoms, sleep problems, and internalizing and externalizing symptoms in children and adolescents with Angelman syndrome. Research in Developmental Disabilities, 128, 104293. Link to article

Geraldine Leader, Amy Hogan, June L. Chen, Leanne Maher, Katie Naughton, Nathan O’Rourke, Mia Casburn & Arlene Mannion (2022) Age of Autism Spectrum Disorder Diagnosis and Comorbidity in Children and Adolescents with Autism Spectrum Disorder, Developmental Neurorehabilitation, 25:1, 29-37. Link to Article

Whelan, S., Mannion, A., Madden, A., Berger, F., Costello, R., Ghadiri, S., Leader, G. (2022) Examining the Relationship Between Sleep Quality, Social Functioning, and Behavior Problems in Children with Autism Spectrum Disorder: A Systematic Review . Nature and Science of Sleep. 14, 675-695 Link to Article

Leader, G., Browne, H., Whelan, S., Cummins, H., & Mannion, A. (2022). Affective problems, gastrointestinal symptoms, sleep problems, and challenging behaviour in children and adolescents with autism spectrum disorder. Research in Autism Spectrum Disorders, 92, 101915. Link to Article

Leader, G., Abberton, C., Cunningham, S., Gilmartin, K., Grudzien, M., Higgins, E., Whelan, S., & Mannion, A. (2022). Gastrointestinal Symptoms in Autism Spectrum Disorder: A Systematic Review. Nutrients, 14(7), 1471. Link to Article